Abstract: In this paper, we examined lipoprotein （a ） Lp（a） and other blood lipids from 150 patients with acute cerebral vessel disease （ACVD） in which there were 51 with cerebral hemorrhage （CH） and 56 multiple site cerebral infarction（MCI ）, 43 lacunar infarct （L1 ）, 42 coronary heart disease（CHD） and 63 hypertension （HT）. The serum Lp （a） concentrations in the patients with MCI and CHD were significantlyhigher than those in age matched control normal subjects（P＜ 0. 01 ）. No relationship between the level of serum Lp （a ） andother blood lipids was found suggesting that serum Lp（a ） maybe an independent risk factor in the development of cardiocerebrovascular disease. The serum ApoB and TC levels in CHwere markedly lower than those of MCI （P＜ 0. 05）.