硝苯地平和比索洛尔治疗原发性高血压前后左室舒张功能的探讨

Effects of Nifedipine and Bisoprolol on Left Ventricular Diastolic Function in Essential Hypertension

摘要: 对原发性高血压患者使用硝苯地平和比索洛尔．与正常血压组进行比较，高血压组比正常血压组舒张早期时相ⅡA－D．ⅡA－MVD间期延长，左室充盈波A增高（P＜0．01），A／R比增加（P＜0．05）。硝苯地平使高血压组舒张功能改善（ⅡA－D．MVO－D缩短（P＜0．01）。比索洛尔使高血压组MVO－D间期延长（P＜0．05），A波振幅降低（P＜0．05），改善左室舒张功能．

Abstract: This study was to assess the effect of nifedipineand bisoprolol in essential hypertension patients group （EH）and normotensives （N ）. Compared with normotensives controlgroup , the left ventricular early diastolic inlerval,ⅡA-D andⅡA-MVO interval and left ventricular filling A wave amplitudeand A/R ratio in hypertensives tvere increased （P＜0. 01）.Nifedipine imprcvcd the left ventricular diastolic function ofEH while bisoprolol signicantly prolonged MVO-D（P＜0. 05）.decreased A wave magnitude （P ＜ 0. 05 ） and improved leftventricular diastolic function.