Abstract: The results of diltiazem （DZ ） treatment in 63cases elderly hypertension patients using two administrationregimes were reported. Group A: 30 cases received DZ 90 mg.once daily, blood pressure （BP） lowered from 182±30/ 116±18mmHg to 147±20/96±18 mmHg （P＜ 0. 01 ）. Group B: 33 cas-es .DZ 60 mg, 3/d,a statistical significant lowering of BP （P＜ 0. 01 ） was also shown. The results showed that a definite antihypertensive effect was achieved by both adiministration methods,with little side-effect. DZ is a safe and raliable drug forthe treatment of essential hypertension, especially for elderlypatients.