高血压右室与左室舒张功能的关系

The Relationship between Right and Left Ventricular Diastolic Function in Essential Hypertension

  • 摘要: 对64例Ⅰ、Ⅱ期临床无心功能不全表现的高血压患者,32例年龄与性别相匹配的健康者,应用多普勒超声心动图技术,对其右室舒张功能进行测定,同时测定其左室收缩及舒张功能并作比较,高血压组按超声心动图标准分为左室肥厚组(LVH)34例,无左室肥厚组(NLVH)30例。测定结果表明,NLVH组与正常组比较,前者通过三尖瓣的E峰较低(P<0.05),A峰较高(P<0.05),E/A比值较小(P<O.01),快速充盈分数(PFF),l/3充盈数(1/3EF)和校正的充盈率峰值(PFR)也降低(P<0.05),下降时间(DT)延长(P<0.01)。LVH组中上述各参数与正常组比较也均有降低,与NLVH组比较A峰、E/A比值和PFR有进一步损害。相关分析发现,右室充盈参数与左室充盈参数密切相关(r从0.45到0.80)。

     

    Abstract: To investigate the relationship between right and left ventricular(RV)diastolic function in patients with essential hypertension,Mmode,two dimensional and pulsed Doppler echocardiography were performed in 64 cases asymptomatic essential hypertensive patients.30 cases of them had normal left ventricular(NLVH)and 34 cases had echocardiography detected left ventricular hypertrophy (LVH).32 normal individuals matched in age and sex served as a control.In all 64 cases hypertensive patients RV systolic function and RV sizes were normal.In 34 cases with LVH,right ventricular early peak velocity(E)was lower(P<0.05);atrial peak velocity(A)were higher(P<0.01)compared to those of normal subjects.Rapid filling fraction(RFF)and 1/3 filling fraction(1/3 FF) and peak filling rate adjusted by stroke volume(PFR) were lower(P<0.05),and deceleration time(DT)was prolonged as well.Diastolic function parameters of LV were well correlated with those of RV.

     

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