高血压患者及其子女红细胞膜ATP酶活性的研究

Erythrocyte Membrane ATPase Activities in Patients with Hypertension and Their Children

  • 摘要: 原发性高血压患者的红细胞膜Na+-K+-ATPase、Ca2+Mg2+-ATPase活性低于正常对照组,但和其子女的测定值无差异,不论EH患者和于女,两种酶活性的改变均与血压不相关。上述结果提示红细胞膜钠泵、钙泵活性低下是EM患者和子女共有的特性。但这种改变可能不是高血压的原因,也不能作为预测高血压发生、发展的参数。

     

    Abstract: Erythrocyte membrane Na+-K+-ATPase and Ca2+-Mg2+-ATPase activities in patient with EH are lower than that in controls,while no significant difference of those two ATPase activities was found between the parent patients and their children.Both Na2+-K+-ATPase and Ca2+-Mg2+-ATPase are not correlated to blood pressure.The resuls indicate that the decreased erythrocyte membrane Na+-K+-ATPase and Ca2+-Mg2+-ATPase activities maybe the common charcteristics of EH patients and their hildren.These properties may not be the causes for hypertension,nor be the predictors for the development of hypertension.

     

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