Abstract: Objective\ To survey the treatment effect of Inhibace on heart failure combined with arrhythmia. Methods\ Clinical diagnosis of cardiomyopathy 13 cases,carditis 11 cases,hypertensive heart failure 9 cases,cardiac infarction 9 cases,and rheumatice heart failure 2 cases were divided in NHYA Ⅱ 7 cases,Ⅲ 29 cases,Ⅳ 8 cases. There are premature beat in 11 cases,atrial fibrillation in 11 cases, ventricular tachycardia or ventricular fibrillation in 4 cases,and heart conductive block in 13 cases. Orally Inhibace 5 mg qd for two weeks and monitored by clincal synptoms and 24 hours Holter determination. Results\ The 41 cases of total 44 patients had the obvious effect（75%） and effectiveness（16%） accoording the health ministry heart diseases therapy standard,otherwhile 3 cases had no effectiveness（3/44）. Conclusion\ Inhibace is a kind of ACEI,it ameliorate the circulating volumes,the loading and electrophysiology of heart muscles,that made the good effect in failure heart and decreased the ocurrence of arrhythmia.