Abstract: Objective To observe the antihypertension effect with enalapril and compare the results with different evaluation methods（A,B,C,D） Methods ABPM were performed before and after treatment with enalapril （10 to 15 mg per day） by single blind study in 58 mild moderate hypertensions for 4 w According three kind of ABPM judgement and CBP ordinary method（A） to analyse the efficacy of enalapril. Results The total response rate（%） of antihypertensive therapy judged by method A?B?C?D were 89 6%?79 3% ?72 5% ?67 2% respectively; The kappa values in comparing A to B,C or D were 0 11,0 04,0 18, respectively and all were no statistic difference（ P ＞0 05）, B to C or D were 0 44 （ P ＜0 05）,0 33 （ P ＞0 05）, C to D was 0 68 （ P ＜0 01）. Specificity and sensitivity of method A were 16 4% and 92 5%,B 41 1% and 87 5%, C 56 7% and 84 2%, D 73 6% and 77 3%,respectively Conclusions Enalapril adiministrated once daily at morning could reduce BP smoothly throughout 24 hours, but different effect rate depends upon the relevant judge method , we believe D method be the best