Abstract: Objective To analyze the effects of comprehensive prevention in different body mass index community population Methods Select 100 thousand populaton in urban Changsha,comprehensive prenvention of cardio and cerebro vascular disease Risk factors surveys were carried out in study population in 2000 and 1997 Result Fat populations（BMI＞25） are increased in the intervention and control communities The risk facors,for example the blood pressure and serum lipid,were the little changes to the population of BMI＞25 and BMI＜18 5,but they were the significant changes after intervention to the populations whose BMI are from 18 5 to 25 Conclusion Comprehensive preventions of cardio and cerebro vascular disease in population are effective, but it is the best way to select the suitable measure to the different population,so made the best effects