Abstract: Objective To explore the relationship between occupational stress factors and hypertension Methods A matched case control study with 96 cases of hypertension and 96 pair matched controls was conducted with occupational stress indication （OSI）, and conditional logistic regression model analysis was used Result It was shown that independent join action appeared to be existed between occupational stress and hypertension OR=2 707, with 95% confidence interval （C I ） of 1 389-5 275, and with a dose effect pattern, when non occupational stress factors were controlled The main occupational stress factors for hypertension were professional features Conclusion This prove further that the occupational stress is an important dangerous factor causing hypertension among the male railway attendants, and the professional features are the main factors of occupational stress