Abstract:
Objective To analyze the electrocardiography(ECG)data of pressure overload-induced cardiac hy pertrophy rats.Methods Pressure overload cardiac hypertrophy was induced by abdominal aorta constriction. Echocardiogram and heart weight measurement demonstrated the occurrence of cardiac hypertrophy.Standardized ECG parameters of limb and chest were measured and statistically analyzed.Results Two weeks after hypertrophy models were established,echocardiogram showed greater LVPWTd,IVSTd,LVDd.ECG showed that left axis deviation and higher R waves in V
A,V
B,V
C(P<0.01),with significant and ubiquitous J point elevation in V
A, V
B,V
C(P<0.01).Conclusion ECG in pressure overload-induced cardiac hypertrophy rats exhibits obviously characteristic features ECG which can be used as one of adjunctive effective and noninvasive methods to evaluate the cardi- ac hypertrophy of rats.