Abstract: Objective To investigate the relationship between overweight/obesity and blood pressure（BP）in Uygur,Kazak,Mongolian and Han populations of Xinjiang BOERTALA region.Methods Three thousand nine hundred thirty-five subjects were selected from the cross-sectional study of metabolism syndrome during September to October in 2004 in Uygur,Kazak,Mongolian and Han populations from BOERTALA region of Xinjiang.The relationships between BP and overweight/obesity,body mass index（BMI）,waist circumference（WC）were investigated by regression analyses.Results After correction for age,gender,education,vocation and drinking factors by multiple linear regression,systolic blood pressure（SBP）increased respectively 6.4（Uygur）,7.4（Kazak）,4.5（Mongolian）,6.2 mm Hg（Han）and diastolic blood pressure（DBP）increased respectively 4.0（Uygur）,5.6（Kazak）,3.5（Mongolian）,4.6 mm Hg（Han）with BMI increasing（from 18.5-23.9,24.0-27.9 to ≥28.0 kg/m 2）（all P ＜0.01）,SBP increased respectively 6.4（Uygur）,6.4（Kazak）,6.3（Mongolian）,5.8 mm Hg（Han）,DBP increased respectively 4.3（Uygur）,5.0（Kazak）,4.0（Mongolian）,3.1 mm Hg（Han）（all P ＜0.01）with WC increasing（from WC＜male 85 cm/female 80 cm,male 85-94 cm/female 80-89 cm to ≥male 95 cm/female 90 cm）.Compared with normal body weight or WC,the risk ratio of hypertension development was 3.6（Uygur）,4.2（Kazak）,2.7（Mongolian）,3.5 mm Hg（Han）times of the four populations with obesity or abdominal obesity.The increase of SBP was lowest in Mongolian（4.5 mm Hg）and was highest in Kazak（7.4 mm Hg）with BMI increasing（from 18.5-23.9,24.0-27.9 to ≥28.0 kg/m 2）,and compared with normal body weight,the risk ratio