Abstract: Objective To investigate the status quo of comorbid clinical diseases prevalence and pharmacologic management of hypertensive outpatients in China. Methods Multi-center cross-sectional study was adopted in this survey. From June to December in 2009,surveys of hypertensive patients were carried out in 46hospitals from twenty two cities of China. At least 100essential hypertensive outpatients were consecutively recruited from each participant hospital according to the consistent inclusion criteria. All subjects were investigated by questionnaires,physical examinations,and biochemical analyses. A total of 5206hypertensive outpatients’ data were included in final analysis. Results Of all hypertensive outpatients,56.0%of them showed obesity,61.5%cases suffered from dyslipidemia,and 42.6% patients had comorbid clinical diseases. The most commonly used antihypertensive therapy was calcium channel blocker which accounted for 57.0%,followed by angiotensin-converting enzyme inhibitor（ACEI）or angiotensin receptor blockers（ARB）. And the least frequently used was diuretics,occupying only8.3%. 51.3% of hypertensive patients with diabetes used ACEI or ARB. And the most commonly used antihypertensive therapy after myocardial infarction was ACEI or ARB（66.5%）,followed byβ-blockers（53.4%）. In hypertensive patients complicated with heart failure or impaired renal function,the application of ACEI and ARB were 67.0%and 57.3%respectively. Conclusions The occurrence of comorbid clinical diseases is high among hypertensive outpatients in China. As for its pharmacologic management,calcium channel blocker and ACEI,or ARB is most frequently used,while diuretics is the least.