Abstract: Objective To investigate the association between serum uric acid（SUA）concentration and cerebral hemorrhage risk in male population. Methods In this cohort study,a total of 76 183men were included and categorized into four groups according to their SUA quartiles levels determined in the health examination during 2006-2007. The candidates were followed up for an average of 4.04years. The effect of SUA concentration on cerebral hemorrhage was estimated by Cox proportional hazard regression analysis. Results In the highest SUA quartile group,subjects had older age,higher body mass index,systolic blood pressure,levels of total cholesterol and triglycerid,higher rates in daily smoking,daily alcohol drinking,lower fasting plasma glucose. They also had more hypertension history,hyperlipidemia history,and antihypertensive or hypoglycemic medication history. The cumulative incidence of cerebral hemorrhage for four SUA quartiles were 0.47%,0.46%,0.44%,and 0.72%,respectively.The univariate Cox proportional hazard regression model showed that the HR（95% CI）of cerebral hemorrhage across SUA quartiles were 1.064（0.782-1.446）,1.010（0.740-1.378）,1.000（reference）,and 1.539（1.159-2.044）,respectively. After the adjustments for age,somking,dringking,blood pressure,blood glucose,blood lipid and other major dieases histories,the multivariate Cox proportional hazard regression model showed that the HR（95% CI）of cerebral hemorrhage across SUA quartiles were 1.043（0.756-1.439）,1.021（0.743-1.403）,1.000（reference）,and 1.393（1.041-1.863）,respectively. Conclusion High SUA is a risk of developing cerebral hemorrhage in male population.