Abstract: Introduction Cardiovascular diseases（CVD）have become one of the major causes of death. Over the past decade,vitamin D has attracted substantial interest towards extra-skeletal role in various disease condition,including CVD. Circulating parathyroid hormone（PTH）is a major regulator of bone and mineral metabolism and stimulates the conversion of vitamin D to its most active form. Several studies suggested PTH not only as a biomarker of vitamin D status but also as an independent cardiovascular risk factor that contributes to the progression of CVD. Objective The objective of this review is to describe the role of disturbances in PTH in relation to CVD.Results Growing evidence suggests a link between higher PTH concentrations and CVD. Few studies indicate that PTH excess may influence underlying mechanism of CVD including cardiac biomarkers,cardiac structure and incident hypertension,which in turn may promote CVD risk. Based on the total evidence in the field,the beneficial effect of vitamin D supplementation by suppressing PTH on cardiovascular health in the general population still needs to be established. Conclusion In conclusion,excess PTH is a common findings among older populations. As higher PTH concentrations may be harmful for cardiovascular health,suppression of PTH-either by vitamin D therapy or more specific PTH suppression-might help to prevent cardiac disease and lower CVD rates.Based on the current evidence,there is no reason to change the current recommendation to improve vitamin D status（and subsequently lower PTH status）of the general population with regard to influencing cardiovascular risk.