Abstract: Objective To explore the factors affecting epicardial adipose tissue（EAT） thickness measured by echocardiography in Beijing community population. Methods One thousand and fifty two community participants with echocardiographic data were enrolled in this study in Gucheng District of Beijing. Waist circumference, body mass index（BMI）, blood pressure, blood glucose and blood lipids were measured, prevalence of cardiovascular diseases were investigated as well. EAT thickness was measured by echocardiography. From the parasternal long-axis view, the fat thickness from the right ventricular free wall to pericardium on the extended line of aortic root during diastole was measured as epicardial fat thickness 1（EAT1）. The maximum fat thickness from right ventricular free wall to pericardium in diastole was measured as epicardial fat thickness 2（EAT2）. Multivariate linear regression analysis was used to analyze the relation between EAT thickness and other factors. Results The means EAT1 of the subjects was（0.39±1.26）cm, which was higher in female than male（0.59±1.55） vs（0.22±0.88）cm. The EAT2 was（0.67±1.76）cm, which was higher in female than male（0.96±2.12） vs（0.41±1.28）cm. Multivariate regression analysis indicated that EAT thickness was correlated with waist circumference, age, heart rate and sex independently（EAT1: waist circumference, β=0.144, age, β=0.086, heart rate, β=0.086, sex, β=0.195; EAT2: waist circumference, β=0.198, age, β=0.175, heart rate, β=0.086, sex, β=0.230; all P＜0.05）. Conclusion Waist circumference, age, heart rate and female were independently influencing factors of EAT thickness measured by echocardiography.