Abstract:
Objective To systematically evaluate the effect of long-term exposure to fine particulate air pollution on the incidence of hypertension in adults. Methods The cohort studies on the effects of long-term exposure to fine paticulate matter(PM
2.5) on hypertension published in China national knowledge infrastructure(CNKI), Wanfang database, PubMed, Embase, Cochrane Library and other databases were searched(the literature retrieval was up to November 2020). Hazard ratio(HR) and its 95%CI were extracted to assess the strength of the association. Subgroup analysis and sensitivity analysis were also performed. Results Seven studies were finally included in the analysis. The overall meta-analysis found that long-term exposure to PM2.5 increased the risk of hypertension, HR=1.11, 95%CI 1.05-1.17 for each 10 μg/m~3 increase in exposure concentration. Subgroup analysis showed that the elder(≥50 years old) and menopause people may be the high-risk group, and there was no significant difference in the risk of hypertension caused by long-term PM
2.5 exposure between Chinese and North American populations and different gender groups. Conclusion There is a positive correlation between long-term PM
2.5 exposure and the occurrence of hypertension.