中国、美国、欧洲儿童血压标准值差异与血压测量次数间差异的比较

A comparative study on the difference in childhood blood pressure criteria among China, the United States and Europe and the difference of blood pressure measurement

  • 摘要: 目的 比较分析中国、美国、欧洲儿童血压标准值差异与实际血压测量结果差异的大小。方法 选取中国、美国、欧洲最新儿童血压标准,通过差值分析和构建血压随身高变化广义可加模型曲线,计算同年龄、性别及实际身高情况下中国、美国、欧洲标准间差值。基于45 314名中国儿童和15 279名美国儿童血压三次测量数据,通过重复测量方差分析计算血压测量差值及95%CI,并与标准间差值进行比较分析。结果 中国、美国、欧洲血压标准差值超过60%分布于-3~3 mmHg。个别年龄组标准值差异较大:中国、美国标准比较,收缩压P95切点在13岁组相差10 mmHg,舒张压P95切点在3岁组相差5 mmHg;中国、欧洲标准比较,收缩压P95切点在16岁差值为9 mmHg,舒张压P95切点差值为6 mmHg。对重复测量血压数据的分析显示,中国男、女生收缩压最大测量差值分别达到3.7和4.1 mmHg,舒张压最大测量差值为2.0和2.1 mmHg;美国男、女生三次测量结果的差值在1 mmHg内。结论 不同国家血压标准值间差异多小于血压多次测量值间差异,血压的准确测量和重复测量比血压标准的选择对个体血压状态的评价更加重要。

     

    Abstract: Objective To compare the difference of blood pressure criteria for children among China, the United States and Europe and the difference in blood pressure measurement. Methods The latest blood pressure criteria for children and adolescents in China, the normal blood pressure standard of the United States, and Europe were used to calculate the differences of blood pressure criteria for the same age, gender, and height by difference analysis and construction of generalized additive model curves for blood pressure change with height. Based on three blood pressure measurements of 45 314 Chinese and 15 279 American children and adolescents, the differences in blood pressure measurements were calculated by repeated-measurement analysis of variance, and which were compared with the differences between criterias. Results More than 60% of the differences in blood pressure standard among China, the United States and Europe were distributed in the range of-3 to 3 mmHg. But in individual age groups, there was a significant difference in standard values: in comparison between standards of Chinese and the United States, the difference of P95 cutoff point for systolic blood pressure was 10 mmHg at the age of 13, and the difference of P95 cutoff point for diastolic blood pressure was 5 mmHg at the age of 3; in comparison between standards of Chinese and European, the difference of P95 cutoff point for systolic blood pressure was 9 mmHg, and that for diastolic blood pressure was 6 mmHg at the age of 16. The analysis of repeated blood pressure data showed that the maximum difference in systolic blood pressure measurement was 3.7 and 4.1 mmHg, and the maximum difference in diastolic blood pressure measurement was 2.0 and 2.1 mmHg for Chinese boys and girls, respectively. while the difference between the three measurements in American boys and girls was within1 mmHg. Conclusion The differences of blood pressure standards between countries are smaller than the differences between multiple measurements of blood pressure, and accurate and repeated measurements of blood pressure are more important for evaluating blood pressure status than the choice of blood pressure standards.

     

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