移动健康管理模式对老年高血压患者干预效果评价的荟萃分析

Effectiveness of mobile health management models in elderly hypertensive patients: a meta-analysis

  • 摘要:
    目的 系统评价移动健康管理模式对老年高血压患者的干预效果,为临床更加规范指导老年高血压患者精准移动健康管理提供依据。
    方法 规范化检索PubMed、Web of Science、万方、中国知网等数据库查找通过移动健康管理对老年高血压患者进行干预的随机对照试验,检索时限从建库起至2025年3月31日。采用 Cochrane 评价工具对纳入的文献进行方法学质量评价。由2名研究者独立筛选文献、提取资料及质量评价,采用RevMan 5.4软件进行荟萃分析。
    结果 共纳入30项随机对照试验(4 286例患者)。荟萃分析结果显示:与常规管理模式相比,应用移动健康管理模式可降低患者收缩压加权均数差(WMD)=−13.46,95%CI:−17.12~−9.80和舒张压(WMD=−7.07,95%CI:−8.34~−5.80),提高血压控制率(RR=1.31,95%CI:1.24~1.38),提高Morisky药物依从性量表评分标准化均数差(SMD)=0.78,95%CI:0.55~1.02。亚组分析结果显示:干预时长≤3个月对血压改善效果更显著,“互联网 + ”多模块综合管理模式优于单一提醒推送模式,具备适老化功能设计的干预(如语音提醒、简化界面)在依从性与血压改善方面更具优势。
    结论 移动健康管理模式可有效改善老年高血压患者的血压控制和用药依从性,为数字医疗在老年慢性病管理中的推广提供了循证支持。受纳入研究质量、数量以及研究结果异质性的限制,未来仍需更多高质量研究进一步验证。

     

    Abstract:
    Objective To systematically evaluate the effectiveness of mobile health (mHealth) management interventions for older patients with hypertension, and to provide evidence for standardizing and guiding precision mHealth management in clinical practice.
    Methods A systematic search was conducted in PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang, and other databases for randomized controlled trials (RCTs) on mHealth interventions in elderly hypertensive patients, from inception to March 31, 2025. Two researchers independently screened the literature, extracted data, and assessed methodological quality using the Cochrane Risk of Bias Tool. Meta-analysis was performed using RevMan5.4.
    Results Thirty RCTs involving 4 286 participants were included. Compared with conventional management, mHealth significantly reduced systolic blood pressure (weighted mean difference WMD = −13.46, 95%CI: −17.12 to −9.80) and diastolic blood pressure (WMD = −7.07, 95%CI: −8.34 to −5.80), and improved blood pressure control rate (RR = 1.31, 95%CI: 1.24 to 1.38), and improved Morisky Medication Compliance Scale score (standardized mean difference SMD = 0.78, 95%CI: 0.55 to 1.02). Subgroup analyses further revealed that interventions with a duration of ≤ 3 months yielded superior blood pressure reductions; “Internet + ” multimodule integrated management showed greater effectiveness than single reminder-based approaches; and age-friendly functional features (including voice reminders, simplified interfaces) were associated with enhanced adherence and more favorable blood pressure outcomes.
    Conclusions mHealth management effectively improves blood pressure control and medication adherence among elderly hypertensive patients, supporting the evidence-based implementation of digital health in chronic disease management for older adults. Given the limitations in methodological quality, quantity, and heterogeneity of included studies, more high-quality RCTs are warranted for further validation.

     

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