Abstract: The diagnostic criteria for hypertension and the need for lower blood lipid targets in high-risk populations have become an important treatment strategy. The guidelines and consensus released in 2025—The 2025 American Heart Association (AHA)/American College of Cardiology (ACC) Guideline for the Management of Hypertension and the 2025 American Association of Clinical Endocrinology Clinical Practice Guideline on Pharmacologic Management of Dyslipidemia—have proposed new standards for blood pressure and blood lipid targets. This article focuses on the current status of blood pressure diagnosis and blood lipid treatment, and proposes our understanding and views on whether blood pressure diagnosis should be below 130/80 mmHg and whether blood lipid targets low density lipoprotein cholesterol (LDL-C) need to be reduced to below 1.4 mmol/L or lower, based on the guidelines and consensus.