Abstract: A 16-year-old male was admitted due to elevated blood pressure detected during physical examination for 16 days. Sixteen days prior to admission, hypertension was identified during a school physical examination, with a recorded blood pressure of 156/107 mmHg. Physical examination upon admission revealed no positive signs. Laboratory findings showed a serum potassium level of 2.98 mmol/L. The aldosterone suppression tests (upright and supine positions) and captopril challenge test were positive. Cortisol rhythm, plasma catecholamines, four-limb synchronous blood pressure measurements, and bilateral adrenal CT were unremarkable. Subsequent genetic testing revealed a mutation in the chloride voltage-gated channel 2（CLCN2）gene. The patient was treated with amlodipine and spironolactone, achieving controlled blood pressure and serum potassium levels.