Abstract: The overall prevalence of secondary hypertension in the hypertensive population is estimated to be no less than 15%. However, there is currently no unified standardized approach for the screening and diagnosis of secondary hypertension etiology within this patient population. It is reasonable, important and feasible to conduct targeted and standardized screening on high-risk population indicated by guidelines strictly according to current guidelines. This consensus provides a comprehensive analysis of the current landscape and gap of secondary hypertension screening and diagnosis both domestically and internationally. Based on the fundamental needs of clinical practice in hypertension management, it aims to explore and establish standardized protocols for the screening and diagnosis of secondary hypertension etiology, thereby contributing to the improvement of diagnostic and therapeutic capabilities for secondary hypertension.