《青少年高尿酸血症与痛风的管理:2025年临床实践共识》解读

Interpretation of clinical practice consensus statement 2025: management of hyperuricemia and gout in adolescents

  • 摘要: 本文解读了中华医学会内分泌学分会新近发表的《青少年高尿酸血症与痛风的管理:2025年临床实践共识》。该共识核心声明包括:青少年高尿酸血症与痛风的诊断标准参考成人;强调生活方式干预为基础,并依据血尿酸水平、是否合并痛风或代谢异常等因素分层制定降尿酸药物治疗策略;青少年痛风发作期的治疗原则等。此外,本文延伸总结了青少年高尿酸血症/痛风合并高血压的综合管理,提出了筛查、分层干预、药物选择及多学科协作的策略。

     

    Abstract: This article interprets the newly published paper Clinical Practice Consensus Statement 2025: Management of Hyperuricemia and Gout in Adolescents by Chinese Society of Endocrinology. The core statements of the consensus include: the diagnostic criteria for hyperuricemia and gout in adolescents adopt adult standards; lifestyle intervention serves as the foundation, and the initiation of urate-lowering therapy is determined based on stratified criteria considering serum uric acid levels, the presence of gout, or metabolic abnormalities; and it outlines the treatment principles for acute gout attacks in adolescents. Furthermore, it also extends to summarize the integrated management of hyperuricemia/gout comorbid with hypertension in adolescents, proposing strategies for screening, stratified intervention, antihypertensive drug selection, and multidisciplinary collaboration.

     

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