Abstract:
Objective To determine age cutoff values for the use of adult hypertension diagnostic criteria in children and adolescents, and to evaluate the consistency and screening effect of the adult criteria with the childhood hypertension diagnostic criteria(gold standard). Methods A literature review and expert consultation were used to determine age cutoff value. In children above the cutoff age, the China Child and Adolescent Cardiovascular Health Survey was used to compare the consistency and screening effect between the adult criteria and the gold standard, and Beijing Blood Pressure Study was used to evaluate the predictive value of childhood hypertension diagnosed by adult criteria and gold criteria for hypertension and subclinical cardiovascular damage in adulthood. Results Adult criteria can be used to evaluate hypertension for children aged 16 and above. Among adolescents aged 16 and above, the adult standard has lower sensitivity(21.1%) but higher specificity(100.0%) compared to the gold standard, with a consensus rate of over 80.0%. And the predictive ability of the adult standard for subclinical cardiovascular health damage in adulthood is also similar to that of the gold standard. Conclusions The age of 16 can be used as a cut-off point for the adoption of adult hypertension diagnostic criteria in children. The use of adult standards for diagnosing childhood hypertension in late adolescence(16-17 years) has certain simplicity and accuracy.