中国青春发育成熟儿童采用成人高血压诊断标准的年龄界值

The age threshold for adopting adult hypertension standards in Chinese mature children and adolescents

  • 摘要: 目的 研究确定儿童青少年(儿童)中采用成人高血压诊断标准的年龄界值,并评价采用成人标准与儿童高血压诊断标准(金标准)的一致性和筛查效果。方法 采用文献综述及专家咨询方法,确定儿童中采用成人高血压标准的年龄界值。在界值点年龄及以上儿童中,通过中国儿童青少年心血管健康调查横断面研究,评价成人标准与金标准的一致性和成人标准的筛查效果;在北京儿童血压队列研究中,评价成人标准和金标准诊断的儿童期高血压对成年高血压及心血管亚临床损害的预测价值。结果 16岁及以上青少年采用成人标准进行诊断。在16岁及以上的青少年中,成人标准比金标准的灵敏度低(21.1%),但特异度高(100.0%),且一致率超过80.0%,对成年期心血管健康亚临床损害的预测能力也与金标准相似。结论 16岁可作为儿童采用成年高血压诊断标准的界值点,且在青春后期(16~17岁)采用成年标准诊断儿童高血压具有一定的简便性和准确性。

     

    Abstract: Objective To determine age cutoff values for the use of adult hypertension diagnostic criteria in children and adolescents, and to evaluate the consistency and screening effect of the adult criteria with the childhood hypertension diagnostic criteria(gold standard). Methods A literature review and expert consultation were used to determine age cutoff value. In children above the cutoff age, the China Child and Adolescent Cardiovascular Health Survey was used to compare the consistency and screening effect between the adult criteria and the gold standard, and Beijing Blood Pressure Study was used to evaluate the predictive value of childhood hypertension diagnosed by adult criteria and gold criteria for hypertension and subclinical cardiovascular damage in adulthood. Results Adult criteria can be used to evaluate hypertension for children aged 16 and above. Among adolescents aged 16 and above, the adult standard has lower sensitivity(21.1%) but higher specificity(100.0%) compared to the gold standard, with a consensus rate of over 80.0%. And the predictive ability of the adult standard for subclinical cardiovascular health damage in adulthood is also similar to that of the gold standard. Conclusions The age of 16 can be used as a cut-off point for the adoption of adult hypertension diagnostic criteria in children. The use of adult standards for diagnosing childhood hypertension in late adolescence(16-17 years) has certain simplicity and accuracy.

     

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