Abstract:
Objective To explore the incidence and influencing factors of hypertension in diabetes patients. Methods The data was derived from 101 510 active and retired employees of Kailuan Group, who took health examination from June, 2006 to October, 2007. Those who with fasting plasma glucose≥ 7.0 mmol/L or those treated diabetes patients with fasting plasma glucose <7.0 mmol/L and blood pressure<140/90 mm Hg were observed. 12 to 39(mean 25.6±4.9) months later, the secondary health examination was carried out. Their blood pressures were measured and the incidence of hypertension was calculated. The influencing factors of hypertension were analyzed by Logistic regression model. Results In the second health examination, there were 908 of 2367 individuals with normotension in the first examination developed into hypertension. The hypertension cumulative incidence was 38.4%, which was higher in males than in females (40.2% vs 31.0%, P<0.01), and in the four age groups (<40, 40-<50, 50-<60 and ≥60) were 28.9%, 34.0%, 40.2% and 43.6%, respectively. After adjustment for other risk factors, binary logistic regression showed that the risk factors of hypertension for diabetes patients were age, male, body mass index(BMI), waist circumference, systolic blood pressure(SBP) and uric acid(respectively, OR 1.167, 1.382, 1.490, 1.220, 2.126, 1.334, P<0.05). Hypertension risk factors for males were age, BMI, SBP, triglycerides and uric acid(respectively, OR 1.141, 1.484, 2.116, 1.239, 1.291, P<0.05), and these for females were age, waist circumference, and SBP (respectively, OR 1.409, 2.131, 2.208, P<0.05). Conclusions Incidence of hypertension in diabetes patients increases with age and differs in genders. Age, male, BMI, waist circumference, SBP, and uric acid are risk factors of hypertension for diabetes patients. Age, BMI, SBP, triglycerides and uric acid affect the hypertension prevalence of males, while age, waist circumferenceand and SBP affect females.