HU Ruiyu, SU Zhaojia, WANG Xianyan, GONG Lansheng. Effects of ACEI Therapy on Insulin Resistance in Patients with Essential HypertensionJ. Chinese Journal of Hypertension, 1994, 2(2). DOI: 10.16439/j.cnki.1673-7245.1994.02.019
Citation: HU Ruiyu, SU Zhaojia, WANG Xianyan, GONG Lansheng. Effects of ACEI Therapy on Insulin Resistance in Patients with Essential HypertensionJ. Chinese Journal of Hypertension, 1994, 2(2). DOI: 10.16439/j.cnki.1673-7245.1994.02.019
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Effects of ACEI Therapy on Insulin Resistance in Patients with Essential Hypertension

    Abstract
  • ACEI （captopril, enalapril and lisinopril ） were administered with dosages as 12. 5 37. 5 mg/d. 5 15 mg/d and 10~30 mg/d,respectively for 4 weeks in 30 patients with essential hypertension. The results showed that the blood pressure decreased from 171/106 mmHg to 143/88 mmHg （P＜0. 001 ）. The blood insulin level and the blood insulin/glucose ratio during glucose loading were significantly reduced, suggesting that ACEI improves the insulin-resistance in patients with essential hypertension.
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