Coronary artery disease and Atherosclerotic Renal Artery Stenosis

ObjectiveTo investigate the relationship between coronary artery disease and atherosclerotic renal artery stenosis（ARAS）as well as pulse pressure and related factors.MethodsFive hundred and fifty-three patients underwent coronary angiography and non-selective renal arteriography.Multiple Logistic regression analysis was used to explore the association of the clinical variables with ARAS.ResultsARAS, defined as a narrowing by more than 50%, was found in 84 patients（15.2%）, while insignificant（＜50% diameter narrowing） stenosis was found in 24 patients（4.3%）.Incidence of ARAS in patients with coronary artery disease（CAD）（22.6% vs 2.0%） and the insignificant stenosis（5.9% vs 1.5%） was higher than that in patients with normal coronary arteries.Multiple Logistic regression analysis revealed that pulse pressure, creatinine and the severity of coronary artery were independent risk factors for ARAS.ConclusionCoronary artery disease was frequently associated with renal artery atherosclerosis.CAD, elevated creatinine concentration and pulse pressure were the independent risk factors of ARAS.