Differences in quality of life between populations with and without high risk for cardiovascular diseases: a propensity score matching analysis

Objective To explore the differences in quality of life between subjects with and without high-risk for cardiovascular diseases（CVD）. Methods Using the survey data of China patient-centered evaluative assessment of cardiac events（PEACE） Million Persons Project in Jiangsu Province from 2015 to 2017, age and gender were matched by 1∶1 propensity score matching（PSM） between the two groups. The inpact of CVD high risk on the quality of life score EuroQol five dimensions questionnaire（EQ-5 D） and EuroQol visual analogue scale（EQ-VAS） was analyzed by multiple linear regression. Results A total of 35 104 subjects（15 948 in high-risk group, 15 657 in non-high-risk group） after PSM from original sample size of 40 243（20 839 in high-risk group, 19 404 in non-high-risk group） were included. Scores of mobility, self-care, routine activities, pain/discomfort, EQ-5 D index score and EQ-VAS score were lower in high-risk group than those in the non-high-risk group（1.9% vs 1.0%, 0.6% vs 0.3%, 1.5% vs 0.8%, 16.8% vs 15.7%, P＜0.05）. There was no statistical difference in anxiety/depression between the two groups（4.5% vs 4.4%, P=0.785）. The EQ-5 D index score and EQ-VAS score of female, elderly, unmarried, junior high school or lower educated, non-smoking, non-drinking, obesity, high blood pressure and dyslipidemia were lower than those of who were not in this state or did not have these diseases（P＜0.05）. The EQ-VAS score of the respondents with annual family income ≤50 000 yuan and diabetes mellitus were lower than that of the population without such condition or this disease（P＜0.001）. After adjusting the basic situation and major chronic diseases, multivariate linear regression showed that EQ-VAS score were lower standardized β values（95% CI）:-0.054（-1.264 to-0.766）. Conclusion High CVD risk population has lower EQ-VAS score. Attention should be paid to the quality of life in high risk population of CVD.